Sample disclosure
This is not a paid review. The supplier provided a free sample of the ZeroSole insole for the original review.
Evidence update: 12 September 2026. The version of the original review sample has not yet been confirmed, so this article does not present its measurements as the specification of the current product.
What is the ZeroSole insole?
ZeroSole uses removable cells so that an area can be selected for targeted pressure relief. Its suitability depends on the individual, the placement of the offloading area, the available shoe space and the instructions for the product version supplied.
What does the research show?
A 2026 paper by Zhang and Lewis evaluated prototype ZeroSole insoles during walking in 15 healthy participants. Average peak pressure in the target area around the second metatarsophalangeal joint fell by 19% with intact prototype insoles and 28% with cavities in both insoles, compared with normal footwear. These were immediate pressure measurements, not proof of long-term lesion healing.
A separate Cardiff Metropolitan University interim product evaluation, dated June 2023, examined customised insoles alongside usual care over six weeks. It reported statistically significant pain reductions, but the reduction in lesion size was not statistically significant. The evaluation excluded people with several higher-risk conditions, including peripheral neuropathy and active or previous foot ulceration.
These findings support further assessment of targeted pressure relief. They should not be generalised to every patient group or treated as proof that the insole corrects pronation or heals foot lesions.
Product version and fit
The product assessed in the older review may differ from the version now supplied. Confirm current dimensions, materials, sizing and intended use with the supplier, then check the fit within the intended footwear. The current ZeroSole product page should not be treated as a measurement of the original review sample.
Practical considerations
- Identify the product version and check its current instructions.
- Check the available shoe space and the effect on fit.
- Place any offloading area as directed and review the result.
- Use clinical assessment for people with foot lesions or higher-risk conditions.
Conclusion
The removable-cell design is relevant to targeted pressure relief. Its suitability depends on the individual, the placement of the offloading area and the available shoe space. Read the evidence alongside the product instructions and a clinical assessment.

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